POST-DOCS
Microbiome Post-docs for Celiac Disease Study at Caltech
We are seeking two talented, motivated individuals to join a collaborative project looking at the role of the microbiome in celiac disease. The multi-institute project aims to test the hypothesis that celiac disease is a heterogeneous disorder, while attempting to define interactions between intestinal epithelial cells, the gut microbiota, immune system, and genetics that underlie differences in clinical presentation, severity of tissue destruction, and the ability to heal. The integration of different layers of molecular (scRNA-seq, genomic), immunological, metabolomics and microbiome data (where host transcriptional and microbial signatures are obtained on the same intestinal biopsy) from clinically well-characterized patients will provide us the unique opportunity to address questions that would not be possible otherwise.
Please see the NIH RePORTER listing for details. The successful post-doc candidates will work in the Ismagilov Lab at the California Institute of Technology to improve understanding of how the mucosal microbiota of the small intestine may drive variation in the clinical phenotype of celiac disease in humans, notably disease severity and healing.
Skills required: Strong microbiology and bioinformatics training; creativity; rigorous scientific training in design and interpretation of research; experience performing amplicon and metagenomic shotgun sequencing and analysis; strong record of prior research accomplishments. Candidates eligible for independent postdoctoral fellowships are encouraged to apply.
Hiring Range: $70,264 per year. The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, experience, qualifications, skills, education, specialty, training, and internal equity. As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off, parental leave, tuition reimbursement, and more.
Candidates should send their CV and a brief statement of their qualifications and research aspirations to rustem.admin@caltech.edu.
Postdoc to work on "Biophysics of the Gut" projects
The Ismagilov Lab at the California Institute of Technology is seeking a postdoctoral researcher to work on projects in the area of "biophysics of the gut." These collaborative projects aim to study the biophysical mechanisms by which polymers (e.g., dietary fibers) impact gut physiology and the microbiome.
For previous work in this research area, please see the following publications from our lab: [doi:10.1039/C9SM00791A], [doi:10.1073/pnas.1602789113], [doi:10.7554/eLife.40387.001], [doi:10.1021/acs.biomac.9b00442].
Skills required: Creativity; rigorous scientific training in design and interpretation of research; strong record of prior research accomplishments. The ideal candidate will have both experimental and conceptual expertise in Soft Matter (e.g., colloids, polymers, and hydrogels). Experience in one or more of gut physiology, animal models, and microbiology would be ideal but is not required. Candidates eligible for independent postdoctoral fellowships are encouraged to apply.
Hiring Range: $70,264 per year. The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, experience, qualifications, skills, education, specialty, training, and internal equity. As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off, parental leave, tuition reimbursement, and more.
Candidates should send their CV and a brief statement of their qualifications and research aspirations to rustem.admin@caltech.edu
GRADUATE APPLICANTS
Prospective graduate students who are interested in joining the lab need to apply for one of the degree options described on the Caltech Graduate Studies Office website. Applicants can find more information on degree options, including Chemical & Chemical Engineering, Bioengineering, Biophysics, Biology & Microbiology, Materials Science, and Applied Physics, here.
CALTECH GRAD-STUDENT ROTATIONS
We welcome inquiries from incoming Caltech graduate students interested in joining or doing rotations in the lab. Please see our Positions page for details of current projects and then contact rustem.admin@caltech.edu.
CALTECH UNDERGRADUATE RESEARCH STUDENTS
Project: Whole genome sequencing of mucosal microbiomes to explore connections with human health and disease
Background: The Ismagilov lab has recently developed many novel methodologies enabling new investigations into how the mucosal microbiome impacts human health and disease. We will be applying these methods to contexts such as microbial biogeography, Celiac Disease, IBD, IBS, and Parkinson's Disease. We also are part of the NIH Human Virome Program and working to define the healthy human virome.
Description: Generation and/or analysis of whole genome sequencing datasets. Suggested Background: Some familiarity with EITHER molecular biology wet lab techniques (pipetting, PCR, etc.) OR coding (python or bash preferred). Interest in human health.
Please email rustem.admin@caltech.edu with your CV and a statement of interests to apply for this position.
GENERAL INQUIRIES
We also welcome general inquiries from current Caltech freshman, sophomore, and junior students who are interested in the work being done in our lab. Students should have the desire and ability to make a substantial time commitment to a project. Please send your CV and a detailed statement of research interests to rustem.admin@caltech.edu.
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